Hyaluronic Acid Therapy Summary
Hyaluronic acid (HA) is a high-molecular-weight polysaccharide, which is widely distributed in the connective tissue extracellular matrix as a companion biomaterial mimicking the same substances found throughout the fluids of various human tissues such as the skin, eyes, joints, connective tissue, and synovium.
Hyaluronic acid, a chief component of the extracellular matrix, is As a naturally occurring part of the synovial fluid and cartilage, it acts as a natural cushion and lubricant in the tissues to help stretch the skin and make it more flexible for reduced skin wrinkles and lines.
Hyaluronic acid gel fillers are injected to restore volume lost due to age or disease, provide facial contour, reduce pain, lubricate the joints, heal wounds faster, reduce scarring and help maintain a youthful appearance.
Hyaluronic Acid Therapy Facts
Low Allergic Response. In its pure form, hyaluronic acid is the same in all organisms and is not species or tissue-specific. Therefore, hyaluronic acid theoretically should not cause an immune response.
Ease of Injections. The hyaluronic acid filler can classify as animal-derived or non-animal derived. Animal-derived fillers come from a rooster comb, and non-animal derived hyaluronic acid production occurs through biofermentation of Streptococcus.
Rapid recovery. Aging leads to decreased production of hyaluronic acid and collagen in the skin. Once the skin has lost its viscoelastic properties, overlying wrinkles begin to form. Hyaluronic acid dermal fillers work to counteract aging by replacing lost volume. In addition to this, hyaluronic acid fillers have also been shown to increase collagen production and affect fibroblast morphology.
Did You Know?
Many different types of hyaluronic acid gel fillers differ in their hyaluronic acid concentration, particle size, cross-linking density, duration, and presence of lidocaine. High-density, large-particle fillers are recommended for deep dermal injections, while the low-density, small-particle fillers are recommended for fine lines.
Non-Surgical Treatment Modality…
Reproducibility. Due to hyaluronic acid’s highly anionic proprieties, it can attract water to swell and create volume and provide structural support.
Immediate results. As a naturally occurring glycosaminoglycan polysaccharide composed of alternating residues of the monosaccharides d-glucuronic acid and N-acetyl-d-glucosamine, which form a linear polysaccharide chain.
Toxicity. The effects of hyaluronic acid filler are reversible with hyaluronidase, an enzyme that breaks down both native and injected hyaluronic acid. Hyaluronidase is particularly useful when the determination is that the filler injection was too superficial, as evidenced by bluish discoloration.
Did You Know?
Several healthcare professionals use hyaluronic acid, including the plastic surgeon, primary care clinicians (including PAs and NPs), dermatologists, and internists, to enhance cosmesis. The hyaluronic acid filler can only be injected by the prescription of a licensed health care provider.
Less Invasive Better Results…
Better Moisture. Hyaluronic acid acts as a biologic humectant, thus retaining water in the skin to maintain moisture and help the tissue regeneration process involved in wound healing.
Macromolecular Tissue. Performs its biological functions according to two primary mechanisms: tissue turnover and as a signaling macromolecule.
Biological Repairman. Plays a multifaceted role in regulating the various biological processes such as skin repairmen, diagnosis of cancer and wound healing.